Spontaneous Tumor Lysis Syndrome due to Uterine Leiomyosarcoma with Lung Metastases

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Spontaneous Tumor Lysis Syndrome due to Uterine Leiomyosarcoma with Lung Metastases

Tumor lysis syndrome (TLS) is an oncologic emergency characterized by a combination of metabolic derangements (hyperuricemia, hyperkalemia, hyperphosphatemia, and hypocalcemia) caused by rapid turnover from cell destruction in certain cancers. These metabolic derangements can lead to seizures, cardiac arrhythmias, renal failure, and death. TLS is usually seen after the initiation of chemotherap...

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Spontaneous tumor lysis syndrome occurring in untreated uterine cancer

•Tumor lysis syndrome is rare in solid tumors.•Tumor lysis syndrome is an oncologic emergency.•We present two cases of spontaneous tumor lysis syndrome arising in uterine cancer.

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Spontaneous Tumor Lysis Syndrome

Tumor lysis syndrome (TLS) is a known complication of malignancy and its treatment. The incidence varies on malignancy type, but is most common with hematologic neoplasms during cytotoxic treatment. Spontaneous TLS is thought to be rare. This case study is of a 62-year-old female admitted with multisystem organ failure, with subsequent diagnosis of aggressive B cell lymphoma. On admission, labo...

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Spontaneous Tumor Lysis Syndrome in Small Cell Lung Cancer

Tumor lysis syndrome (TLS) is a life-threatening oncologic complication caused by the lysis of a vast number of malignant cells resulting in metabolic derangements and organ dysfunction. TLS can occur spontaneously before initiation of any therapies often referred to as spontaneous tumor lysis syndrome (STLS), or shortly after the induction of chemotherapy, radiotherapy, or cytolytic antibody t...

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Uterine leiomyosarcoma with central nervous system metastases

Leiomyosarcoma (LMS) is a rare tumour and comprises 2-3% of all malignant uterus neoplasms [1]. Leiomyosarcoma is characterised by aggressive behaviour, high recurrence rates, and poor overall survival, despite multimodal treatment [3]. Surgery is the main treatment and consists of total abdominal hysterectomy. A randomised trial consisting of 224 patients diagnosed with uterine sarcomas stage ...

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ژورنال

عنوان ژورنال: Case Reports in Critical Care

سال: 2017

ISSN: 2090-6420,2090-6439

DOI: 10.1155/2017/4141287